Getting ready to run my first game

I am the type that likes to build all of the terrain and accessories for the RPGs I run. I have either purchased hard copies or PDF versions of books and such and am not exactly sure where to physically start in the game. I have five players who will run their own characters and I plan to basically start them at level one. What’s a good narrative for these people(?) all hooking up together in the first place?

I thought I might just let them move towards some sort of settlement to try and interact with it so that they can come across some sort of quest there, but it is that beginning narrative I am struggling with. In the video game, you’re a loaner that meets people along the way. These guys will all be hooked up from day one.

Just looking for ideas.